Children at daycare

11 Daycare Centers in Sikeston, Missouri

Browse all 11 daycare centers in Sikeston, Missouri. Compare options and find the right childcare for your family.

Top 10 Best Rated Daycares in Sikeston

Ranked using a weighted score that combines Google rating with the number of parent reviews — daycares with more reviews rank higher than those with a high rating but few reviews. Last updated: March 2026.

  1. 1

    604 Elm St, Sikeston, MO · Before or After School Daycare · Capacity: 20 children

    Parents praise the YMCA facility for its clean, well-maintained environment and friendly, welcoming staff. The facility offers excellent amenities including a pool, gym, sauna, and track at affordable membership rates. Parents appreciate the free daycare option while working out and note the family-friendly atmosphere.

    Clean facilitiesfriendly and professional staffaffordable membership fees ($65/month family)free 2-hour daycare
  2. 2

    100 Twitty Dr, Sikeston, MO · Before or After School Daycare · Capacity: 20 children

    Parents praise this YMCA facility for its excellent facilities, cleanliness, and outstanding customer service. Staff members are consistently described as friendly, welcoming, and professional. The center offers great value with affordable membership rates and comprehensive amenities for families.

    Clean facilitiesfriendly and professional stafflarge indoor poolwell-maintained gym with free weights and machines
  3. 3

    1310 E Salcedo Rd, Sikeston, MO · Child Daycare & Preschools · Capacity: 20 children

    Reviews praise the YMCA facility for its cleanliness, friendly and professional staff, and comprehensive amenities including a pool, gym, sauna, and track. Parents appreciate the family-friendly environment, affordable membership rates, and complimentary childcare options. The center is consistently described as welcoming and well-maintained.

    Clean facilitiesfriendly and professional stafflarge indoor poolcomprehensive gym equipment
  4. 4

    115 S West St, Sikeston, MO · Headstart Programs · Capacity: 200 children

    Parents consistently praise Delta Area Economic Opportunity Corporation for being helpful and supportive to families in need. The facility is noted for assisting working families and making a positive community impact. One parent mentioned a staffing issue related to appointment scheduling.

    helpful staffcommunity supportassists working familiesresponsive to needs
  5. 5

    640 Colonel George E. Day Parkway, Sikeston, MO · Child Daycare & Preschools · Capacity: 75 children

    Delta South Children's Center receives mixed reviews with ratings ranging from 1-5 stars. Some families praise the staff's kindness and attention during transitions, while others report concerns about resident care quality, staff conduct, safety protocols, and management issues.

    Thoughtful and kind staffnice facilitygood support during family transitions

Top Rated

Highest rated daycares in Sikeston based on parent reviews

Ymca Of Southeast Missouri Matthews Elementary

4.6(20)

604 Elm St, Sikeston, MO

Parents praise the YMCA facility for its clean, well-maintained environment and friendly, welcoming staff. The facility offers excellent amenities including a pool, gym, sauna, and track at affordable membership rates. Parents appreciate the free daycare option while working out and note the family-friendly atmosphere.

Clean facilitiesfriendly and professional staffaffordable membership fees ($65/month family)

Ymca Of Southeast Missouri 5th/6th Grade Center

4.6(20)

100 Twitty Dr, Sikeston, MO

Parents praise this YMCA facility for its excellent facilities, cleanliness, and outstanding customer service. Staff members are consistently described as friendly, welcoming, and professional. The center offers great value with affordable membership rates and comprehensive amenities for families.

Clean facilitiesfriendly and professional stafflarge indoor pool

Ymca Of Southeast Missouri Kindergarten Center

4.6(20)

1310 E Salcedo Rd, Sikeston, MO

Reviews praise the YMCA facility for its cleanliness, friendly and professional staff, and comprehensive amenities including a pool, gym, sauna, and track. Parents appreciate the family-friendly environment, affordable membership rates, and complimentary childcare options. The center is consistently described as welcoming and well-maintained.

Clean facilitiesfriendly and professional stafflarge indoor pool

Lil' Bulldogs Child Care Center

5(2)

307 N Prairie St, Sikeston, MO

Delta Area Economic Opportunity Corporation

4.4(12)

115 S West St, Sikeston, MO

Parents consistently praise Delta Area Economic Opportunity Corporation for being helpful and supportive to families in need. The facility is noted for assisting working families and making a positive community impact. One parent mentioned a staffing issue related to appointment scheduling.

helpful staffcommunity supportassists working families

Rainbow Daycare Ctr

4(2)

612 W North St, Sikeston, MO

Map

Daycare Centers in Sikeston, Missouri

There are 11 daycare centers in Sikeston, Missouri. Below you'll find a complete directory to help you compare and choose the right daycare for your child.

When choosing a daycare in Sikeston, consider visiting facilities in person, checking their licensing status, and asking about staff-to-child ratios, daily routines, and safety policies.

All Daycare Centers in Sikeston

Showing 11 results

Lil' Bulldogs Child Care Center
Child Daycare & Preschools
5
Address
307 N Prairie St, Sikeston, MO
Phone
(573) 472-6468
Ymca Of Southeast Missouri Matthews Elementary
Before or After School Daycare
4.6

Parents praise the YMCA facility for its clean, well-maintained environment and friendly, welcoming staff. The facility offers excellent amenities including a pool, gym, sauna, and track at affordable membership rates. Parents appreciate the free daycare option while working out and note the family-friendly atmosphere.

Clean facilitiesfriendly and professional staffaffordable membership fees ($65/month family)
Address
604 Elm St, Sikeston, MO
Phone
(903) 824-6833
Ymca Of Southeast Missouri 5th/6th Grade Center
Before or After School Daycare
4.6

Parents praise this YMCA facility for its excellent facilities, cleanliness, and outstanding customer service. Staff members are consistently described as friendly, welcoming, and professional. The center offers great value with affordable membership rates and comprehensive amenities for families.

Clean facilitiesfriendly and professional stafflarge indoor pool
Address
100 Twitty Dr, Sikeston, MO
Phone
(573) 427-1825
Ymca Of Southeast Missouri Kindergarten Center
Child Daycare & Preschools
4.6

Reviews praise the YMCA facility for its cleanliness, friendly and professional staff, and comprehensive amenities including a pool, gym, sauna, and track. Parents appreciate the family-friendly environment, affordable membership rates, and complimentary childcare options. The center is consistently described as welcoming and well-maintained.

Clean facilitiesfriendly and professional stafflarge indoor pool
Address
1310 E Salcedo Rd, Sikeston, MO
Phone
(573) 620-0718
Delta Area Economic Opportunity Corporation
Headstart Programs
4.4

Parents consistently praise Delta Area Economic Opportunity Corporation for being helpful and supportive to families in need. The facility is noted for assisting working families and making a positive community impact. One parent mentioned a staffing issue related to appointment scheduling.

helpful staffcommunity supportassists working families
Address
115 S West St, Sikeston, MO
Phone
(573) 471-8320
Rainbow Daycare Ctr
Child Daycare & Preschools
4
Address
612 W North St, Sikeston, MO
Phone
(573) 472-1174
Delta South Children'S Center LLC
Child Daycare & Preschools
3.3

Delta South Children's Center receives mixed reviews with ratings ranging from 1-5 stars. Some families praise the staff's kindness and attention during transitions, while others report concerns about resident care quality, staff conduct, safety protocols, and management issues.

Thoughtful and kind staffnice facilitygood support during family transitions
Address
640 Colonel George E. Day Parkway, Sikeston, MO
Phone
(573) 475-4585
Ymca Of Southeast Missouri Lee Hunter Elementary
Before or After School Daycare
Address
315 Baker Ln, Sikeston, MO
Phone
(573) 931-4682
Ymca Of Southeast Missouri Southeast Elementary
Before or After School Daycare
Address
2300 Ables Rd, Sikeston, MO
Phone
(573) 419-9736
Delta Area Economic Opportunity Corporation
Headstart Programs
Address
123 Arthur, Sikeston, MO
Phone
(573) 379-3841
Helping Hand Day Care
Child Daycare & Preschools
Address
124 N West St, Sikeston, MO
Phone
(573) 472-3299

Page 1 of 1· 11 results

Frequently asked questions

There are 11 all daycares in Sikeston, Missouri. Browse our directory to compare options and find the right fit for your child.
When choosing a daycare in Sikeston, consider visiting facilities in person and checking:
  • Licensing status with Missouri's regulatory agency
  • Staff-to-child ratios (requirements vary by age group in Missouri)
  • Safety measures and cleanliness
  • Daily routines and educational curriculum
  • Parent reviews and ratings
  • Location and hours that fit your schedule
Sikeston offers several types of childcare facilities:
  • Child Daycare & Preschools — 5 facilities
  • Headstart Programs — 2 facilities
  • Before or After School Daycare — 4 facilities
Each type serves different needs — center-based facilities typically offer structured programs, while head start programs are federally funded for low-income families.
Daycare costs in Missouri typically range from $200 to $400 per week for full-time care, depending on the child's age, facility type, and location within the state. Infant care tends to be more expensive due to lower staff-to-child ratio requirements. Contact individual facilities in Sikeston for current pricing.
Yes, daycare centers in Sikeston must be licensed by Missouri's childcare licensing agency. Licensed facilities are required to meet standards for safety, health, staff qualifications, and staff-to-child ratios. You can verify a facility's license status through your state's licensing database.